CLINICAL TRIALS

Clinical Trials


Consensus Guidelines for Clinical Trial Design

The Radiosurgery Society® (RSS) supports collaborative groups and individuals to develop and share clinical and research protocols for stereotactic radiosurgery (SRS), stereotactic body radiation therapy (SBRT) and emerging advanced therapy modalities.

The Consensus Guidelines for Clinical Trial Design is a new platform for expert groups to post consensus concepts on proposed clinical trial recommendations and solicit review and feedback from the medical, physics and science community through the RSS Public Comment Survey. The goal of the Consensus Guidelines for Clinical Trial Design is to encourage the development of clinical trials in SRS/SBRT and advanced radiation therapy modalities through common understanding and consensus on the design elements of clinical trials.

Below you will find all the details of the first project.


SFRT for Head & Neck Cancer

Consensus Guidelines for the Design of Clinical Trials in Spatially Fractionated Radiation Therapy for Head and Neck Cancer

Open for Public Comment January 4, 2021 - January 18, 2021


Spatially fractionated radiation therapy (SFRT) using GRID and Lattice therapy, a form of radiation therapy that uses highly non-uniform doses for the treatment of tumors, has shown much promise in early clinical studies for improving tumor control and reducing side effects in bulky advanced cancers. However, prospective multi-institutional clinical trials to investigate this technique further are needed.

The RSS GRID/Lattice, Microbeam and Flash Radiotherapy Working Groups have established an SFRT Clinical Trial Design Consensus effort to help encourage and streamline the development of clinical trials in SFRT for specific tumors. Read about the guideline development process.

A Consensus Guideline for Clinical Trial Design in SFRT for Head and Neck Cancer has been developed by an expert panel of the Working Groups. You are invited to review a draft of the Consensus Guideline for Clinical Trial Design in SFRT for Head and Neck Cancer and provide your comments by completing the survey by January 18, 2021.



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