New RSSearch Registry Publication on Stereotactic Ablative Radiation Therapy (SABR) for Adolescent and Young Adult Malignancies


SAN JOSE, Calif., September 12, 2024 – We are thrilled to announce the latest publication evaluating stereotactic ablative radiation therapy (SABR) for adolescent and young adult patients enrolled in the RSSearch Patient Registry, the longest established patient registry dedicated to SRS/SBRT managed by a professional society. The study reveals that SABR is a promising treatment option for children and young adults with certain types of tumors. The article “Stereotactic Ablative Radiation Therapy (SABR) for Adolescent and Young Adult Malignancies" by Raj Singh, M.D., et al. was published on August 14, 2024 in Cureus. DOI: 10.7759/cureus.66890

The study, led by a Raj Singh, MD, Assistant Professor, Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, focused on assessing the local control, overall survival and outcomes for SABR for treating primary tumor recurrences and metastatic tumors in patients aged to 16 to 39 years . The researchers concluded that higher doses of SABR were associated with improved local control, particularly those with sarcoma primaries. In contrast, poorer outcomes were associated with central nervous system primaries and spinal metastases.


"The RSSearch Patient Registry is an extremely valuable resource in its heterogeneity among participating centers in treatment planning across both academic and community settings. This allows one to report on real-world outcomes of patients and also to examine relevant questions to radiation oncologists, notably dose-response relationships."
- Raj Singh, M.D., Assistant Professor of Radiation Oncology, The Ohio State University Comprehensive Cancer Center / The James Cancer Hospital and Solove Research Institute


While SABR is already widely used for adult patients with certain cancers, its application in pediatric oncology has been limited due to concerns about long-term side effects and potential impacts on development. This new research aims to help fill that gap, providing critical data that sheds light to the use of SABR as a treatment option for younger patients.

About the RSSearch Patient Registry
The Radiosurgery Society hosts the RSSearch Patient Registry, a multi-platform research and data sharing registry that has become a critical resource for radiosurgical investigators world-wide in a wide range of specialties, as well as hospitals, teaching institutions and researchers engaged in the field. Since RSSearch opened in 2005, the data has served as the foundation for peer-reviewed publications and research; improved quality of patient care; elevated medical decision making; provided access to novel treatments and approaches; and advanced the science of SRS/SBRT. Data mined from RSSearch also contributes to the industry-wide development of clinical and quality guidelines. To date, the RSSearch Registry includes nearly 35,000 cases from 50+ international centers.

We welcome new centers to participate in the RSSearch Registry. To learn more, contact registry@therss.org.

View the RSSearch Registry Bibliography

About the Radiosurgery Society®
The Radiosurgery Society (RSS) – a non-profit, independent, multi-disciplinary organization of surgeons, radiation oncologists, physicists, and allied professionals, who are dedicated to advancing the science and clinical practice of radiosurgery. Originally formed in 2002 and becoming 501(c)(6) in 2008, the Radiosurgery Society today (www.therss.org) represents members who perform stereotactic body radiotherapy and radiosurgery in hospitals and freestanding centers throughout the world.


Contacts:
Stephanie Tomei
The Radiosurgery Society®
PressRelease@therss.org